In the ever-evolving world of ‘clean-label’ cosmetics, the development of novel preservation techniques is crucial for ensuring product efficacy and safety. High-pressure and microwave processing are emerging as innovative methods that offer significant advantages over traditional preservation techniques.
A recent article from University Putra Malaysia, titled “Formulation of Anti-Acne Gel Containing Citrus aurantifolia (Christm.) and Aloe barbadensis (L.) Extracts and Evaluating the Impact of High-Pressure and Microwave Processing” exemplifies the potential of these cutting-edge preservation methods for parabens replacement and the impact of the treatment on the gel’s physical stability.
The key steps of the study:
- Phytochemical Analysis of the herbal extracts:
- The quantitative evaluation of plant extracts showed that lime ( aurantifolia) had higher levels of phenolics, flavonoids, tannins, and ascorbic acid than aloe vera (A. barbadensis).
- Furthermore, the GC-MS technique identified multiple bioactive compounds with antimicrobial properties in both extracts.
- Gel Formulation:
- Once characterized, they use 1% of each plant extract with Carbopol-940 as the gelling agent.
- The formulated gel was evaluated for physicochemical properties and compared with a commercial herbal formulation.
- The developed formulation was odorless, translucent, washable, homogeneous, and lump-free.
- It also showed good spreadability, viscosity, extrudability, stability, and a high percentage of drug content.
- The formulated gel showed greater inhibition against Staphylococcus aureus, it means a superior an antibacterial activity than the commercial product.
- Physical analysis of treated (high-pressure & microwaved) gels
- High-pressure (600 MPa, 120 s) and microwave (700 W, 80 s) treatments were effective alternatives to parabens.
- Furthermore, high pressure and microwave pasteurization processes improved the viscosity and spreadability of the gel (without paraben) and resulted in like the paraben-containing normal gel.
- Both treated gels maintained stability over 4 weeks, comparable to paraben-containing formulations (commercial one and paraben-containing gel).
Conclusion
With this new finding, it is concluded that the formulated washable and skin-permeable herbal anti-acne gel containing C. aurantifolia and A. barbadensis has a high potential as a cosmeceutical. By harnessing the power of non-thermal processing methods, researchers have paved the way for more natural and potent solutions. These advanced technologies not only enhance the stability and shelf-life of cosmetic products but also preserve the integrity of active ingredients, leading to cleaner formulations in acne treatment.
Have questions about implementing HPP for your skin care products? We’d love to hear from you! Share your thoughts and questions by contacting our HPP food science team at [email protected]
