{"id":64483,"date":"2025-06-13T12:50:05","date_gmt":"2025-06-13T10:50:05","guid":{"rendered":"https:\/\/www.hiperbaric.com\/?p=64483"},"modified":"2025-06-13T13:03:14","modified_gmt":"2025-06-13T11:03:14","slug":"hpp-and-microwave-processing-alternatives-for-clean-label-anti-acne-gel","status":"publish","type":"post","link":"https:\/\/www.hiperbaric.com\/en\/hpp-and-microwave-processing-alternatives-for-clean-label-anti-acne-gel\/","title":{"rendered":"HPP and Microwave Processing: Alternatives for Clean-Label Anti-Acne Gel"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\" wp-image-64494 aligncenter\" src=\"https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-300x169.png\" alt=\"\" width=\"635\" height=\"358\" srcset=\"https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-300x169.png 300w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-1024x576.png 1024w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-768x432.png 768w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-1536x864.png 1536w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-1260x709.png 1260w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-630x354.png 630w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-420x236.png 420w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-840x473.png 840w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4-315x177.png 315w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-4.png 1920w\" sizes=\"(max-width: 635px) 100vw, 635px\" \/><\/p>\n<p>In the ever-evolving world of<strong> \u2018clean-label\u2019 cosmetics<\/strong>, the development of novel preservation techniques is crucial for ensuring product efficacy and safety. High-pressure and microwave processing are emerging as <strong>innovative methods<\/strong> that offer significant advantages over traditional preservation techniques.<\/p>\n<p>A recent article from University Putra Malaysia, titled &#8220;<a href=\"https:\/\/jms.mabjournal.com\/index.php\/mab\/article\/view\/3152\">Formulation of Anti-Acne Gel Containing <em>Citrus aurantifolia<\/em> (Christm.) and <em>Aloe barbadensis <\/em>(L.) Extracts and Evaluating the Impact of High-Pressure and Microwave Processing<\/a>&#8221; exemplifies the potential of these cutting-edge preservation methods for parabens replacement and the impact of the treatment on the gel\u2019s physical stability.<\/p>\n<h2><strong>The key steps of the study:<\/strong><\/h2>\n<ol>\n<li><strong>Phytochemical Analysis of the herbal extracts:<\/strong><\/li>\n<\/ol>\n<ul>\n<li>The quantitative evaluation of plant extracts showed that <strong>lime<\/strong> (<em> aurantifolia<\/em>) had higher levels of phenolics, flavonoids, tannins, and ascorbic acid than <strong>aloe vera<\/strong> (<em>A. barbadensis<\/em>).<\/li>\n<li>Furthermore, the GC-MS technique identified multiple bioactive compounds with <strong>antimicrobial properties<\/strong> in both extracts.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\" wp-image-64434 aligncenter\" src=\"https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-3-300x38.png\" alt=\"\" width=\"758\" height=\"96\" srcset=\"https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-3-300x38.png 300w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-3-768x98.png 768w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-3-630x80.png 630w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-3-420x53.png 420w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-3-840x108.png 840w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-3-315x40.png 315w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-3.png 850w\" sizes=\"(max-width: 758px) 100vw, 758px\" \/><\/p>\n<ol start=\"2\">\n<li><strong>Gel Formulation:<\/strong><\/li>\n<\/ol>\n<ul>\n<li>Once characterized, they use 1% of each plant extract with Carbopol-940 as the gelling agent.<\/li>\n<li>The formulated gel was evaluated for <strong>physicochemical properties<\/strong> and compared with a commercial herbal formulation.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\" wp-image-64452 aligncenter\" src=\"https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-4-1-300x106.png\" alt=\"\" width=\"790\" height=\"279\" srcset=\"https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-4-1-300x106.png 300w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-4-1-768x271.png 768w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-4-1-630x222.png 630w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-4-1-420x148.png 420w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-4-1-840x296.png 840w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-4-1-315x111.png 315w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/Table-4-1.png 850w\" sizes=\"(max-width: 790px) 100vw, 790px\" \/><\/p>\n<ul>\n<li>The developed formulation was odorless, translucent, washable, homogeneous, and lump-free.<\/li>\n<li>It also showed good spreadability, viscosity, extrudability, stability, and a high percentage of drug content.<\/li>\n<li>The formulated gel showed greater inhibition against <em>Staphylococcus aureus<\/em>, it means a superior an <strong>antibacterial activity<\/strong> than the commercial product.<\/li>\n<\/ul>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignright wp-image-64460 \" src=\"https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-300x246.png\" alt=\"\" width=\"289\" height=\"237\" srcset=\"https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-300x246.png 300w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-1024x839.png 1024w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-768x629.png 768w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-1260x1032.png 1260w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-630x516.png 630w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-420x344.png 420w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-840x688.png 840w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379-315x258.png 315w, https:\/\/www.hiperbaric.com\/wp-content\/uploads\/2025\/06\/HPP-Food-Science-Newsletter-1-e1749804777379.png 1318w\" sizes=\"(max-width: 289px) 100vw, 289px\" \/><\/p>\n<ol start=\"3\">\n<li><strong>Physical analysis of treated (high-pressure &amp; microwaved) gels<\/strong><\/li>\n<\/ol>\n<ul>\n<li>High-pressure (600 MPa, 120 s) and microwave (700 W, 80 s) treatments were effective alternatives to parabens.<\/li>\n<li>Furthermore, high pressure and microwave pasteurization processes <strong>improved the viscosity and spreadability<\/strong> of the gel (without paraben) and resulted in like the paraben-containing normal gel.<\/li>\n<li>Both treated gels maintained <strong>stability over 4 weeks<\/strong>, comparable to paraben-containing formulations (commercial one and paraben-containing gel).<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><strong>Conclusion<\/strong><\/h2>\n<p>With this new finding, it is concluded that the formulated washable and skin-permeable herbal anti-acne gel containing <em>C. aurantifolia<\/em> and <em>A. barbadensis<\/em> has a high potential as a cosmeceutical. By harnessing the power of <strong>non-thermal processing methods<\/strong>, researchers have paved the way for more natural and potent solutions. These advanced technologies not only <strong>enhance the stability and shelf-life <\/strong>of cosmetic products but also preserve the<strong> integrity of active ingredients<\/strong>, leading to cleaner formulations in acne treatment.<\/p>\n<p>Have questions about implementing HPP for your skin care products? We&#8217;d love to hear from you! Share your thoughts and questions by contacting our HPP food science team at <a href=\"mailto:apps@hiperbaric.com\">apps@hiperbaric.com<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the ever-evolving world of \u2018clean-label\u2019 cosmetics, the development of novel preservation techniques is crucial for ensuring product efficacy and safety. High-pressure and microwave processing are emerging as innovative methods that offer significant advantages over traditional preservation techniques. A recent article from University Putra Malaysia, titled &#8220;Formulation of Anti-Acne Gel Containing Citrus aurantifolia (Christm.) and&#8230;<\/p>\n","protected":false},"author":7,"featured_media":64502,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[254,253,259],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>HPP and Microwave Processing: Alternatives for Clean-Label Anti-Acne Gel - Hiperbaric<\/title>\n<meta name=\"description\" content=\"High-pressure and microwave processing are emerging as innovative methods that offer significant advantages over traditional preservation techniques.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hiperbaric.com\/en\/hpp-and-microwave-processing-alternatives-for-clean-label-anti-acne-gel\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HPP and Microwave Processing: Alternatives for Clean-Label Anti-Acne Gel - 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