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  • Surrogate microbe

    A non-pathogenic species and strain responding to HPP treatment in a manner equivalent to a pathogenic species and strain. The surrogate allows biological verification of an HPP treatment without introducing pathogens into a food processing area. For example, PA 3679 is used as a surrogate microbe for C. botulinum in thermal process validation. Listeria innocua is a possible surrogate for L. monocytogenes in HPP process validation.