HIGH PRESSURE PROCESSING (HPP) is a non-thermal pasteurization method that can be applied to cosmetic and pharmaceutical products.

Pharma-Cosmetic videos

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For more information please download HPP Pharma-Cosmetic pdf


Some HPP product examples

  • Pharma

HPP main advantages in the pharma-cosmetic sector are:

  • Greater safety without heat treatment: Drastically reduces the overall spoiling and pathogenic flora.
  • Extends shelf life maintaining functional properties and activity of thermo sensitive molecules (vitamins, proteins...)
  • Vaccine production: inactivation of pathogens (bacteria, virus) while saving its antigen response intact.
  • Production of new formulas: hypoallergenic, fewer preservatives...
  • Disaggregation and controlled re-naturalization of proteins of therapeutic interest.
  • HPP can be used to process a wide range of products: liquid and semisolid, emulsions, gels, etc. either middle products or the final product already in its commercial package.

Scientific Literature

  • Aertsen, A.; Meersman, F.; Hendrickx, M. E. G.; Vogel, R. F. & Michiels, C. W. Biotechnology under high pressure: applications and implications. Trends in Biotechnology 2009, 27(7), 434–441. 
  • Masson, P.; Tonello, C. & Balny, C. High pressure biotechnology in medecine and pharmaceutical science. Journal of Biomedicine and Biotechnology 2001, 1(2), 85–88. 
  • Qoronfleh, M. W.; Hesterberg, L. K. & Seefeldt, M. B. Confronting high-throughput protein refolding using high pressure and solution screens. Protein Expression and Purification 2007, 55(2), 209–224.